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Berberine Hi Tech Pharmaceuticals is a groundbreaking supplement that leverages the power of berberine to support blood sugar metabolism and healthy weight management. This article will provide an in-depth analysis of the research conducted by Hi-Tech Pharmaceuticals on their Nexrutine XS Berberine product. We will explore the unique features of this supplement, including its improved bioavailability and the proprietary Cyclosome delivery system.

Introducing the groundbreaking Berberine Best Weight Loss Supplement Capsules by Hi-Tech! Get ready to unlock your weight loss goals like never before. Our cutting-edge Nexrutine XS Berberine offers improved bioavailability, making it 10 times more effective than traditional berberine supplements. Experience enhanced retention time, with results lasting over 10 hours! Say goodbye to poor oral bioavailability and hello to a new level of effectiveness. With Hi-Tech's innovative formula, your weight loss journey just got a whole lot easier. Don't miss out on this exciting breakthrough - grab your Berberine Best Weight Loss Supplement Capsules today and start achieving your dream body!

Understanding Berberine Bioavailability

Bioavailability is a crucial factor in determining the effectiveness of any supplement. Traditional berberine extracts have poor oral bioavailability and bioabsorption profiles. However, Hi-Tech Pharmaceuticals' Nexrutine XS Berberine has overcome this limitation, showing a significant improvement in berberine bioavailability. The company's pharmacokinetic study demonstrated over 10 times higher berberine bioavailability on a molar basis compared to standard berberine products. (1)

The increased bioavailability of Nexrutine XS Berberine is attributed to its unique formulation, which addresses the challenges posed by berberine's poor oral absorption. By improving the retention time from 30-45 minutes to over 10 hours, Nexrutine XS Berberine ensures a sustained release of berberine in the body, maximizing its effectiveness.

The Benefits of Nexrutine XS Berberine

Nexrutine XS Berberine offers a wide range of benefits that support metabolic health, blood sugar regulation, cardiovascular health, immune function, weight management, and gastrointestinal health. Let's delve into each of these benefits in detail: (2)

Blood Sugar & Cardiovascular Support

Nexrutine XS Berberine favorably modulates insulin response, leading to improved blood sugar profiles. It helps level both blood glycemic and insulin levels, promoting better glucose control. This supplement also optimizes the blood lipid profile, promoting healthy cholesterol levels and reducing the risk of cardiovascular diseases. (3)

Immune Support

Berberine has long been recognized for its immune-supporting properties. Nexrutine® XS Berberine harnesses the power of berberine to enhance immune function, helping the body combat infections and maintain overall well-being.

Weight Management & GI Support

Maintaining a healthy weight is a significant concern for many individuals. Nexrutine XS Berberine plays a positive role in body composition by inducing the redistribution of adipose tissue. Additionally, it promotes healthy gastrointestinal function, aiding digestion and supporting overall gut health. (4)

The Technology Behind Nexrutine XS Berberine

Hi-Tech Pharmaceuticals utilizes its proprietary Cyclosome technology in the development of Nexrutine® XS Berberine. This technology is a breakthrough in enhancing the bioavailability of compounds. The Cyclosome® delivery system ensures that the body can effectively absorb the plant extracts as they pass through the gastrointestinal tract.

The key components of Cyclosome include a special structure of sunflower lecithin and cyclodextrin. This unique combination allows for the entrapment of hydrophobic compounds, such as berberine, in water-soluble cyclodextrin complexes within liposomes. This process facilitates the delivery of berberine and other active ingredients to the systemic circulation, bypassing first-pass inactivation in the liver. (5)

The Advantages of Cyclosome Technology

Cyclosome technology offers several advantages over conventional delivery systems. Unlike simple coatings that provide minimal protection and limited absorption, Cyclosome ensures a higher percentage of usable ingredients reaches the bloodstream. This innovative technology enables the delivery of a wide array of ingredients to the systemic circulation through the intestinal lymphatic route, bypassing first-pass metabolism in the liver.

By enhancing the bioavailability of berberine and other compounds, Cyclosome technology allows for more efficient utilization of ingredients without the need for high dosages. This not only improves the effectiveness of the supplement but also enhances safety by minimizing the risk of overdosing.

Suggested Use and Precautions

To experience the benefits of Nexrutine XS Berberine, it is recommended to take two tablets 2-3 times daily or as directed by a healthcare professional. However, it is crucial to consult with a physician before starting any new supplement regimen, especially if you are pregnant, nursing, taking medications, or have a medical condition.

It is important to note that Nexrutine XS Berberine is not intended for individuals with impaired glucose metabolism, such as diabetes. This supplement should not be used as a substitute for medical recommendations and should be used in conjunction with a balanced diet and regular exercise.


Nexrutine XS Berberine from Hi-Tech Pharmaceuticals represents a significant advancement in berberine supplementation. With its improved bioavailability and the use of Cyclosome technology, this supplement provides a natural and effective solution for supporting blood sugar metabolism, cardiovascular health, immune function, weight management, and gastrointestinal well-being. As with any supplement, it is important to consult with a healthcare professional before starting a new regimen.

Supplement Facts

Serving Size: 1 tablet
Servings Per Container: 100

Nexrutine XS Berberine Cyclosome 250g
(stem/bark) phellodendron amurense standardized to contain 97% berberine (phellodendron 50:1 extract equivalent to 12.5g of dried bark and stems)

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